Orthopedic situations can affect individuals in Los Angeles of all ages and lifestyles. While many orthopedic injuries are attributable to sudden and severe accidents that inflict a serious toll on joints and bones, most are caused by general wear and tear of the joint. Through the gradual loss of cartilage and the weakening of very important connective tissues, joints can lose their regular functions and endure from extreme ache during even gentle physical activity.

While many go for joint replacements and various in-depth surgeries yearly, an increasing number of individuals understand the huge array of makes use of and advantages from regenerative medicine. This course of takes advantage of the most important steps made in medical care in recent times, offering patients in Los Angeles with newer and more practical remedies.

Whether you could have been suffering from orthopedic conditions for years or are only simply beginning to really feel the toll on your joints, regenerative medicine remedy may be right for you. Los Angeles Orthopedic surgeon Steven W. Meier, MD and the staff at Meier Orthopedic Sports and Regenerative Medicine provide quite a few types of regenerative drugs treatment in order to assist patients put an end to numerous bodily limitations. To study more about regenerative medication remedy methods and schedule an appointment with an skilled orthopedic surgeon, call (310) 777-7845 or contact us on-line in the present day.

How Can Regenerative Medicine Assist you?

Rather than exchange missing tissue in joints with synthetic supplies, joint regenerative medicine focuses solely on regenerating tissue, tendons, cartilage, bone, and ligaments. Whether these tissues have been severely damaged or have lost appreciable mass, regenerative methods aim to restore important tissue to a healthier and younger state.

So as to provide the most effective therapies possible for every patient’s unique orthopedic situation, Dr. Meier in Los Angeles provides three predominant modalities of regenerative medicine. Each of these remedies regrows tissue in a distinct method and could also be most suitable for certain conditions.

Prolotherapy

Because orthopedic circumstances can cause severe pain that limits actions throughout both professional and personal life, prolotherapy remedy is designed to alleviate critical discomfort in a pure manner. During prolotherapy treatment, an answer that features dextrose is injected between the muscles and bone where the harm has taken place. A numbing spray is used in the course of the therapy, making this a painless procedure.

The solution that's injected into the problem area not only quickly alleviates ache but is designed to stimulate the manufacturing of tendons and ligaments. Additionally, the immune system can be stimulated, bringing fibroblasts into the areas the place ache happens, which is able to both eradicate pain and develop comfortable tissue.

Depending on the type and severity of an harm, a patient may endure multiple prolotherapy treatments. However, the whole healing time is commonly far shorter and far much less difficult than post-surgery rehabilitation. With the assistance of a skilled orthopedic surgeon, a Prolotherapy remedy plan might be tailored to your distinctive orthopedic condition.

As an orthopedic surgeon who practices using prolotherapy, Dr. Meier supplies a uncommon mixture of abilities, as prolotherapy in Los Angeles isn't usually part of the usual coaching curriculum for orthopedic surgical procedure close to Beverly Hills. As well as, the mixture of prolotherapy use with surgical procedure skills is advantageous, as a surgeon has detailed data of anatomical construction. The mix of a excessive degree of technical skill and expertise performing prolotherapy remedy means there is a diminished threat of complications and can even cut back the entire amount of therapies needed for efficient prolotherapy care. Additional information about regenerative medication treatment might be found on our prolotherapy FAQ.

Stem Cell and PRP Therapy

Stem cells are the building blocks of the human physique. Modern scientific research has proven that stem cells are utilized by the physique to turn into something that is required on a daily basis. However, the human physique is not equipped to create substitute tissues for orthopedic accidents by itself.

Through orthopedic stem cell therapy therapy, we use these cells to develop tissue has been broken or misplaced. The amniotic stem cells have the flexibility to grow into almost any kind of tissue in little time, thanks to modern medical procedures. By doing so, we are able to particularly create what your joints want to be able to return them to a wholesome and correctly functioning state.

Additionally, using platelet-wealthy plasma (PRP) therapy in stem cell remedies allows orthopedic surgeons to supercharge self-healing capabilities. During this process, blood will probably be drawn from the affected person, then spun down to concentrated platelets and progress factors. This concentrated plasma will then be injected immediately into the injured joint, tendon, or ligament, which can expose harm to this pure healing solution. PRP therapy treatment is amongst the most fashionable and leading edge of all procedures obtainable. medlineplus.gov has extra information about stem cell therapy as effectively.

Platlet-Rich Plasma for the Shoulder

What Conditions are Treatable with PRP Therapy?

There are quite a few situations that may be handled with PRP Therapy. While no two patients will bear the identical remedy for his or her wants, understanding what circumstances are treatable by means of regenerative medication treatment can enable you make an informed choice regarding your path to restoration.

The following orthopedic circumstances can all be treated through numerous types of regenerative drugs:

- Chronic Neck and Back Pain
- Shoulder Tendinopathy
- Degenerative & Rheumatoid Arthritis - Shoulder, Knee, Hip, and Spinal
- Elbow Epicondylitis (Tennis Elbow/Golfers Elbow)
- Knee Patellar Tendinosis (Runner Knee/Jumpers Knee)
- Knee Chondromalacia
- Achilles Tendinosis
- Plantar Fasciitis
- Tendonitis and Tears - Achilles, Hip, Knee, Rotator Cuff, and Patellar
- Ankle Sprains & Instability
- Bursitis
- Cartilage Defects
- Degenerative Disc Disease
- Facet Joint Syndrome
- Failed Back Surgery
- Foot Pain
- Ligament Injuries
- Neck Pain
- Occipital Neuralgia
- Osteoarthritis - All Joints
- Pes Anserine Bursitis
- Plantar Fasciitis
- Runners Knee
- Sacroiliac Joint Pain
- Scoliosis
- Tarsal Tunnel Syndrome
- Trochanteric Bursitis
- Whiplash
Must you be affected by symptoms indicating that you've any of those situations, or in case you have been diagnosed with a situation, it's vital that you just seek help from a talented orthopedic surgeon. Dr. Steven W. Meier of Los Angeles not solely gives regenerative medication injection therapy and a wide number of orthopedic services, he additionally supplies second opinions on diagnoses in order to provide patients essentially the most info doable on their circumstances to obtain correct joint tissue regeneration.

Surgery and Regenerative Medicine

At Meier Orthopedic Sports and Regenerative Medicine in Los Angeles, we advocate a multimodal strategy to the remedy of musculoskeletal circumstances. This means combining greater than only one sort of treatment to provide an enhanced end result. Combining surgical procedures with regenerative medication is an ideal means of optimizing treatment outcomes.

We prefer to not restrict our Los Angeles patients’ potential by depriving them from any therapy approaches that may be useful for his or her condition. No one type of remedy is good at every little thing. Each remedy modality has its personal inherent strengths and limitations. For example, a surgical reconstruction may efficiently stabilize a joint and stop further damage however it might not remove all signs of pain and inflammation. Regenerative injection therapy (RIT) on the other hand, may present additional pain relieving properties that the surgical procedure does not by lowering chronic inflammation. In this fashion, the restrictions of 1 modality are compensated for by the strengths of a complementary therapy whose weaknesses are, in flip, canceled out by the first. Using totally different modalities like this that work collectively to achieve a greater outcome than using simply one among them alone known as synergy. Synergy in therapy is one of the best ways to realize the greatest outcomes potential.

Learn more about what Dr. Steven Meier can do to your orthopedic recovery through regenerative medication. Call (310) 777-7845 or fill out the web contact form to study more about what Meier Orthopedic Sports and Regenerative Medicine can do for you!

Regenerative Therapies Help Restore "Normalcy" After Surgery

"Homeostasis" is: the tendency toward a comparatively stable equilibrium between interdependent parts, especially as maintained by physiological processes.

No matter how refined a surgeon’s approach is, surgical procedure continues to be essentially a traumatic insult to the anatomic site, stirring up inflammation and upsetting the natural steadiness of the joint. RIT helps normalize and restore homeostasis to joint shortly after surgery.

Stimulate Faster Healing

The human body has an amazing capacity for healing itself. However, healing takes time. In everyday life, there are plenty of widespread situations and stresses that can further prolong the duration of healing together with internal biologic and environmental sources. Stem cell and PRP therapy have been shown to speed up tissue healing which can assist velocity up and shorten the restoration time after surgery.1 This means less ache, less inconvenience and earlier return to regular actions of each day dwelling with much less threat of complications such as infection, stiffness, blood clots, and many others.

Certainly one of many examples of that is in reconstructive ligament surgery. Anterior cruciate ligament (ACL) surgery of the knee is commonly performed and is associated with a prolonged recovery and rehabilitation period. Regenerative injection therapy has been proven to considerably speed up this restoration process. In a clinical examine by Radice et al., use of PRP with ACL reconstruction surgery reduced the time for graft maturation by half (179 days vs. 369 days). In different words, that is approximately 6 months vs. 12 months for "ligamentization". 2 Speeding up the healing course of can mean much less postoperative ache and sooner return to sports activities and an energetic life-style.

Stimulate Better Healing

Rotator Cuff Repair

Certain sorts of injuries and circumstances are recognized to be very resistant to healing. Rotator cuff tears are infamous for this. Rotator cuff repair surgery is related to a excessive price of healing failure. Clinical studies reveal the rate of recurrent or residual tears after rotator cuff repair surgery to range from 20-82% of circumstances. 2-9 Even after a superbly performed surgical procedure, the tendon often doesn't heal completely because rotator cuff tendon tissue has very poor blood supply. By "priming" the system and augmenting the biologic healing response, the speed of profitable tendon healing may be significantly improved.

In a examine by Hernigou et al., the impact of mesenchymal stem cells (MSCs) on rotator cuff repair surgical procedure was investigated.10 One group of patients undergoing rotator cuff repair surgical procedure was treated with MSCs from bone marrow aspirate (BMA) on the time of surgery whereas the other group acquired no stem cells. By 6 months, there was 100% healing in the MSC treated group vs. solely 67% healing within the non-MSC handled group. By 10 years after surgery, 87% of the repairs in the MSC treated group still remained intact vs. solely 44% within the non-MSC treated group.

Fractures

Certain bony fractures are known to take a long time to heal or could also be prone to not heal and grow to be non-unions. This may be as a result of severity of the damage and/or anatomic location. Bones that may be vulnerable to nonunion include the clavicle, scaphoid, femur, tibia and fifth metatarsal to call just a few. Tseng et al. demonstrated how the use of stem cells can promote and speed up bony healing. Eleven Patients who want to accelerate the healing course of or those with fractures as risk for delayed healing or non-healing may consider using stem cell therapy.

Regenerate Tissue

Meniscus Tears

Meniscus cartilage tears in the knee are extraordinarily common. Arthroscopic surgery offers essentially the most successful modality in coping with these lesions. Approximately 80% of meniscus tears are usually not repairable which means the damaged meniscus tissue must be removed throughout arthroscopic surgery. The remaining 20% of meniscus tears are amenable to surgical repair. Since the broken tissue of a meniscus tear is a noxious irritant, removing this unstable tissue from non-repairable meniscus tears usually leads to superb ache relief within the brief time period. However, for the reason that meniscus serves as an important shock absorber within the knee, shedding a portion of this structure topics the knee to increased inner stresses that can accelerate the event of painful degenerative arthritis years later. It's generally misunderstood that merely having arthroscopic surgical procedure can "cause" arthritis later. Provided the surgical procedure is performed correctly, this is totally not true. It's at the moment the meniscus tear occurs that the injury is finished and that tissue is no longer offering mechanical help to the knee. The arthroscopic surgery merely removes the nonfunctional offending irritant leaving the remaining, viable portion of the meniscus intact. After losing a portion of their meniscus to a tear, it would be most beneficial to the individual’s long-term prognosis to be able to regenerate that deficient tissue. Stem cell therapy holds the promise of doing simply that. In a examine by Vangsness et al., meniscus regeneration was observed in patients treated with MSCs after arthroscopic surgical procedure whereas the group of patients receiving surgical procedure but no stem cells showed no regeneration. 12

In circumstances where torn meniscus restore could also be possible, it is all the time preferable to repair the meniscus in order to preserve as a lot of the shock absorber tissue as potential. However, meniscus healing tends to be very poor since a lot of the meniscus has very little blood provide. Historically, this has resulted in a high fee of restore failure requiring revision surgical procedure and eventual tissue removing. Stem cell expertise provides the opportunity to stimulate the required healing that must follow restore surgery. Several research have shown that the usage of MSCs stimulates the healing of meniscus tissue. 13, 14 15

Provide Better Stability to Joints

Ligament Reconstruction Using Allograft Tissue

A ligament reconstruction will be carried out using either the patient’s personal tissue (autograft tissue) or tissue from an organ donor (allograft tissue). Using autograft is traditionally thought of the "gold standard" since higher healing is predicted with native tissue. However, there are downsides to harvesting one’s own in any other case normal and practical tissue equivalent to muscle weakness, residual ache and additional threat of surgical complications equivalent to infection and stiffness. Using MSCs together with allograft tissue, though, can present increased stimulation to healing making results with allograft comparable to that of autograft. In some cases, the MSC-allograft combination can perform even better and with larger consistency than autograft alone. 16, 17 And with allograft, of course, the patient can keep away from detrimental aspects of autograft harvest.

Ligament Reconstruction and Treating Secondary Stabilizers

When a patient sustains an acute ligament injury in Los Angeles, many structures are injured. Ligament reconstruction surgical procedure usually focuses on rebuilding solely the primary ligament involved. This can mean that other joint stabilizing structures still remain lax. When these secondary buildings are lax, this places quite a lot of stress on the newly reconstructed ligament. This focus of stress on one construction can lead to stretching out of the reconstructed ligament.

For instance, when an ACL ruptures throughout a knee harm, damage also occurs to the joint capsule or "envelope" and different secondary restraints such because the anterolateral ligament (ALL). 18 ACL reconstruction surgical procedure restores only the ACL but none of the secondary stabilizers. Without the assistance of the secondary stabilizers, this could result in stretching out of the ACL graft. However, after ACL reconstruction surgical procedure, these essential accessory stabilizing constructions will be "tightened up" with prolotherapy therapies postoperatively in order to allow a extra balanced and full stabilization of the knee with additional assist for the newly reconstructed ACL.

Reduce Pain

Arthroscopic Surgery with Concurrent Osteoarthritis

Many patients who undergo surgical procedure for tender tissue accidents additionally occur to have degenerative joint illness (DJD) or osteoarthritis associated with the aging process and natural put on-and-tear. This applies to many people since DJD is so common. While the surgical procedure usually fixes the torn ligament or tendon efficiently, these patients may nevertheless go on to experience residual painful inflammation postoperatively due to the roughened cartilage of DJD. A great solution is to combine the surgery with a regenerative injection therapy like stem cell or PRP.

Cole et al. found that patients with osteoarthritis had important pain relief at 6 months and 12 months after PRP injection therapy when in contrast to regulate teams.19 This pain relief was even found to be superior to patients who acquired hyaluronic acid injections (i.e. Synvisc, Orthovisc, Hyalgan).

Van Buul et al. demonstrated that PRP reduces the inflammation related to osteoarthritis.21 Drengk et al. reported that PRP stimulates growth of cartilage cells.20 Anz et al. found that both PRP and BMA had an anti-inflammatory impact on osteoarthritic knees leading to ache reduction. While the ache relief from PRP was good, the results of the MSCs in BMA was even better.22

Reduce Scar Tissue Formation Leading to Less Stiffness & More Cosmetic Incisions

Joint stiffness as a consequence of excessive scar tissue formation after damage or surgical procedure may be a problem for some patients. This may end up in a protracted rehabilitation interval and probably never regaining full mobility within the concerned joint. Stem cell therapy can scale back stiffness after surgical procedure by selling the regeneration of normal, supple tissue in favor of less desirable, robust scar tissue. This effect can also promote extra cosmetic surgical incisions.

Liu et al. showed that MSCs forestall hypertrophic scar formation by regulating the inflammatory course of.23 Jackson et al. demonstrated that by attenuating inflammation within the wound and reprogramming the native immune and wound healing cells, MSCs favor native tissue regeneration and inhibit fibrotic scar tissue formation. 24

Reduce Complications

Certainly one of the good features of stem cell therapy is its excellent security profile. It is one of few medical remedies that's related to nearly no significant unwanted side effects. Along with being a really protected therapy by itself, it also can reduce the chance of complications from other concurrent remedy comparable to surgical procedure by enhancing healing and warding off infection.

Infection Prevention

Using stem cell therapy and PRP can protect patients from developing a postoperative infection. Infection is a recognized potential complication of surgical procedure and may end up in prolonged recovery, revision surgery, the need for long-term antibiotic treatment, extra scarring and a compromised practical result. Through the activity of concentrated platelets and leukocytes, the propagation of potentially infectious organisms is restricted by stem cell preparations and PRP.

Stem cell solutions and PRP have natural antimicrobial properties against many sorts of frequent micro organism. Mei et al. discovered that in a stem cell experimental group, there was an up-regulation of genes involved in selling phagocytosis (the ingestion of micro organism by cells of the immune system) and bacterial killing.25 Li et al. demonstrated that in vitro, PRP suppressed the expansion of bacterial colonies.26 They identified that not like conventional antibiotics, PRP could also be superior because it does not induce microbial resistance. Moojen et al. discovered that PRP, within the type of a platelet-leukocyte gel, whereas protected for the affected person additionally has strong bacteriocidal (bacteria-killing) activity making it a potentially useful substance to combat in opposition to postoperative infections.27 It is clear that utilizing stem cells and PRP concurrently with surgery in Los Angeles has the potential to forestall infection and to reduce the need for expensive post-operative remedy, significantly with implant-associated infections.

Learn extra about regenerative medicine at stemcells.nih.gov.

Find Treatment in your Needs

If you are searching for a solution to help along with your orthopedic limitations, get in touch with Dr. Steven W. Meier and the medical team at Meier Orthopedic Sports and Regenerative Medicine. Dr. Meier is a Board-certified orthopedic surgeon with years of experience in superior orthopedic methods.

For extra info on regenerative drugs and what treatments may be right for you, contact an orthopedic surgeon by calling (310) 777-7845 or filling out the web contact kind. Through an appointment with a regenerative medication specialist at Meier Orthopedic Sports and Regenerative Medicine in Los Angeles, you can restore your physique and keep healthy for years to come.

Next, study our Lipogems.

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Steven Meier, MD

Dr. Steven Meier is a renowned board certified orthopedic surgeon specializing in regenerative sports medication and arthroscopic surgery. Dr. Meier believes in treating every patient individually in line with their needs.

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