Tricyclic antidepressants (TCAs) were among the first antidepressants. While they have been largely replaced by SSRIs, SNRIs, and other antidepressants, TCAs can still be a good option in cases where people have not responded to other types of antidepressant drugs. Most SSRIs are similar in regard to how well they work, although there may be subtle differences that can make one a better choice for you.

GoodRx Health aims to provide the best answers for health questions online. Powered by an expert team of leading doctors, pharmacists, and healthcare experts with resources to empower consumers to be their own health advocates. GoodRx has helped consumers save over $30 billion and has been committed to making healthcare more affordable and accessible for over a decade. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use mirtazapine only for the indication prescribed.

Antipsychotics are not FDA approved for or typically used for anxiety disorders. These are typically approved and presribed for psychotic disorders like schizophrenia. However, many of them are also approved and prescribed for bipolar disorders. Thus, they may be good choices for patients with schizophrenia or bipolar and also anxiety. These include (but are not limited to) diphenhydramine (aka Benadryl) and xylazine test strip hydroxyzine (aka Vistaril). Other classes of medicines sometimes have mild antihistamine effects too (e.g. some antipsychotics or mirtazapine).

Research suggests that antidepressants can be helpful for people with moderate or severe depression. Stephanie Robilio is an accomplished Clinical Director at Agape Behavioral Healthcare. With a Master of Social Work degree, LCSW license, and extensive training in Rapid Resolution Therapy under her belt, she brings a wealth of expertise to her role. Her unique combination of education and experience allows her to provide exceptional care to clients and lead her team with confidence. Stephanie’s joy comes from witnessing the moments when her patients creatively connect the dots and bravely move toward reclaiming their power. Her purpose is to help individuals understand their past so they can create a future full of hope, growth, and success.

MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, tranylcypromine, and others. Drinking alcohol can increase certain side effects of mirtazapine. Lindsey Konkel is an award-winning freelance journalist with more than 10 years of experience covering health, science, and the environment.

Medication-assisted therapy is the combination of medication and therapy used to help someone overcome specific feelings or specific behavior. This is typically a great option for people with alcohol abuse disorder. Some medications professionals prescribe to people with alcohol abuse include disulfiram, naltrexone, and acamprosate. Overall, it is extremely difficult to handle and properly treat alcoholism and depression. This is why it is imperative to catch both diseases early so that doctors and other medical health professionals can help create the best course of action for the patient. Having discontinuation symptoms doesn’t mean you’re addicted to your antidepressant.